Secondary Osteoporosis in Patients with Juvenile Idiopathic Arthritis

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Secondary Osteoporosis in Patients with Juvenile Idiopathic Arthritis

Bone disease in patients with juvenile idiopathic arthritis (JIA) is associated with focal (joint erosion and juxtaarticular osteopenia) and systemic bone loss (generalized osteopenia or reduction of bone mass density). Pathophysiology of bone loss is multifactorial and involves particularly proinflammatory cytokines and deleterious effects of glucocorticoid therapy. Clinical studies in patient...

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Clinical and Serological Findings in Juvenile Patients with Idiopathic Arthritis in Southwestern of Iran

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Background: Systemic-onset Juvenile Idiopathic Arthritis (SoJIA) is an autoinflammatory disease with complex genetic trait starts in children less than 16 years of age with fever and cutaneous rash. Despite, the main genetic factors that may play a role in SoJIA have not yet been identified. High level of interleukin-1beta in the blood of SoJIA patients has been reported. The production and sec...

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Juvenile idiopathic osteoporosis.

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ژورنال

عنوان ژورنال: Journal of Osteoporosis

سال: 2011

ISSN: 2042-0064

DOI: 10.4061/2011/569417